September 11, 1961 - Hurricane Carla struck the Texas Coast to the east of Port Lavaca, Texas, bringing heavy rainfall and wind damage to the Houston area.

August 1973 - "Houston Mass Murders" occur. 27 boys are killed by 3 men.

July 1978 - Race Riots occur in the Moody Park section of the city (in response to the drowning of Jose Campos Torres by two Houston Police officers, and are documented by KPRC-TV, whose reporters are attacked and injured during their report.

August 18, 1983 - Hurricane Alicia hits Houston and Galveston.

April 16, 1997 - Doris Angleton is murdered in her River Oaks home. Her husband, Robert Angleton, and his brother, Roger Angleton, would be suspected for the crime.

June 4, 1999 - Noemi Dominguez was shot dead in her home by Angel Maturino Resendiz, a serial killer.

June 5 – June 9, 2001 - Tropical Storm Allison devastates the Houston area flooding much of the city including the Central Business District, several cultural institutions and major hospitals and research facilities in the Texas Medical Center. The storm is called a 500-year event.